Emerging respiratory infections: The infectious disease pathology of SARS, MERS, pandemic influenza, and Legionella.
Identifieur interne : 000B50 ( Main/Exploration ); précédent : 000B49; suivant : 000B51Emerging respiratory infections: The infectious disease pathology of SARS, MERS, pandemic influenza, and Legionella.
Auteurs : Benjamin T. Bradley [États-Unis] ; Andrew Bryan [États-Unis]Source :
- Seminars in diagnostic pathology [ 0740-2570 ] ; 2019.
Descripteurs français
- KwdFr :
- Grippe humaine (anatomopathologie), Grippe humaine (diagnostic), Humains, Infections de l'appareil respiratoire (anatomopathologie), Infections de l'appareil respiratoire (diagnostic), Infections à coronavirus (anatomopathologie), Infections à coronavirus (diagnostic), Légionellose (anatomopathologie), Légionellose (diagnostic), Syndrome respiratoire aigu sévère (anatomopathologie), Syndrome respiratoire aigu sévère (diagnostic).
- MESH :
- anatomopathologie : Grippe humaine, Infections de l'appareil respiratoire, Infections à coronavirus, Légionellose, Syndrome respiratoire aigu sévère.
- diagnostic : Grippe humaine, Infections de l'appareil respiratoire, Infections à coronavirus, Légionellose, Syndrome respiratoire aigu sévère.
- Humains.
English descriptors
- KwdEn :
- Coronavirus Infections (diagnosis), Coronavirus Infections (pathology), Humans, Influenza, Human (diagnosis), Influenza, Human (pathology), Legionellosis (diagnosis), Legionellosis (pathology), Respiratory Tract Infections (diagnosis), Respiratory Tract Infections (pathology), Severe Acute Respiratory Syndrome (diagnosis), Severe Acute Respiratory Syndrome (pathology).
- MESH :
Abstract
Lower respiratory infections remain one of the top global causes of death and the emergence of new diseases continues to be a concern. In the first two decades of the 21st century, we have born witness to the emergence of newly recognized coronaviruses that have rapidly spread around the globe, including severe acute respiratory syndrome virus (SARS) and Middle Eastern respiratory syndrome virus (MERS). We have also experienced the emergence of a novel H1N1 pandemic influenza strain in 2009 that caused substantial morbidity and mortality around the world and has transitioned into a seasonal strain. Although we perhaps most frequently think of viruses when discussing emerging respiratory infections, bacteria have not been left out of the mix, as we have witnessed an increase in the number of infections from Legionella spp. since the organisms' initial discovery in 1976. Here, we explore the basic epidemiology, clinical presentation, histopathology, and clinical laboratory diagnosis of these four pathogens and emphasize themes in humans' evolving relationship with our natural environment that have contributed to the infectious burden. Histology alone is rarely diagnostic for these infections, but has been crucial to bettering our understanding of these diseases. Together, we rely on the diagnostic acumen of pathologists to identify the clinicopathologic features that raise the suspicion of these diseases and lead to the early control of the spread in our populations.
DOI: 10.1053/j.semdp.2019.04.006
PubMed: 31054790
Affiliations:
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Le document en format XML
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In the first two decades of the 21st century, we have born witness to the emergence of newly recognized coronaviruses that have rapidly spread around the globe, including severe acute respiratory syndrome virus (SARS) and Middle Eastern respiratory syndrome virus (MERS). We have also experienced the emergence of a novel H1N1 pandemic influenza strain in 2009 that caused substantial morbidity and mortality around the world and has transitioned into a seasonal strain. Although we perhaps most frequently think of viruses when discussing emerging respiratory infections, bacteria have not been left out of the mix, as we have witnessed an increase in the number of infections from Legionella spp. since the organisms' initial discovery in 1976. Here, we explore the basic epidemiology, clinical presentation, histopathology, and clinical laboratory diagnosis of these four pathogens and emphasize themes in humans' evolving relationship with our natural environment that have contributed to the infectious burden. Histology alone is rarely diagnostic for these infections, but has been crucial to bettering our understanding of these diseases. Together, we rely on the diagnostic acumen of pathologists to identify the clinicopathologic features that raise the suspicion of these diseases and lead to the early control of the spread in our populations.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Washington (État)</li></region><settlement><li>Seattle</li></settlement><orgName><li>Université de Washington</li></orgName></list><tree><country name="États-Unis"><region name="Washington (État)"><name sortKey="Bradley, Benjamin T" sort="Bradley, Benjamin T" uniqKey="Bradley B" first="Benjamin T" last="Bradley">Benjamin T. Bradley</name></region><name sortKey="Bryan, Andrew" sort="Bryan, Andrew" uniqKey="Bryan A" first="Andrew" last="Bryan">Andrew Bryan</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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